c-Met (phospho Tyr1234) antibody [HL2907]-单抗-深圳欣博盛生物科技有限公司

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c-Met (phospho Tyr1234) antibody [HL2907]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX640244	规格：100μl	目录价：￥4000
货号：GTX640244-S	规格：25μl	目录价：￥1700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

c-Met (phospho Tyr1234) antibody [HL2907]

别名:

MET proto-oncogene, receptor tyrosine kinase , AUTS9 , DFNB97 , HGFR , RCCP2 , c-Met

反应种属:

Human

宿主来源:

Rabbit

实验应用:

靶标/特异性:

This antibody detects c-Met when singly phosphorylated at Tyr1234 or dually phosphorylated at Tyr1234 and Tyr1235, but it does not recognize c-Met when singly phosphorylated at Tyr1235.

同种型:

IgG

免疫原:

Carrier-protein conjugated synthetic peptide surrounding phospho Tyr1234 of human c-Met. The exact sequence is proprietary.

克隆性:

Monoclonal

克隆号:

HL2907

纯化方式:

Affinity purified by Protein A.

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, no preservatives.

生产商:

GeneTex

功能与背景:

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]

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