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折扣/货期| 货号：GTX42600 | 规格：100μg | 目录价：￥8900 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
C4c antibody [10-12]
别名:
C4B1 Antibody , CO4 Antibody , C4B2 Antibody , C4BD Antibody , C4B3 Antibody , C4B Antibody , complement component 4B (Chido blood group) Antibody , CPAMD3 Antibody , CH Antibody , C4B5 Antibody , C4F Antibody , C4B12 Antibody
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, FCM, IHC-Fr, WB
同种型:
IgG1
免疫原:
Purified human C4c.
克隆性:
Monoclonal
克隆号:
10-12
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Borate buffered saline, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq, Jul 2008]
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