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折扣/货期| 货号：V5630SAF-100UG | 规格：100 ug | 目录价：￥6652.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Cadherin 2 Antibody / CDH2 / N-Cadherin
产品描述:
Recognizes a protein of ~140kDa, identified as N-Cadherin (NCAD), also known as CD325. NCAD is a member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently deregulated in cancer cells. Studies have linked N-cadherin to cancer metastasis by showing the aggressive tumor cells had preferentially turned-on N-cadherin as opposed to E- or P-cadherin.
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P, WB
同种型:
Mouse IgG2b, kappa
免疫原:
A portion of amino acids 400-600 from human Cadherin 2 protein was used as the immunogen for the Cadherin 2 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
CDH2/9488
纯化方式:
Protein G affinity
保存温度:
Aliquot the Cadherin 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
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