官网链接
折扣/货期| 货号：GTX641517 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX641517-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CaMKII alpha (phospho Thr286) antibody [HL3570]
别名:
calcium/calmodulin dependent protein kinase II alpha , CAMKA , CaMKIINalpha , MRD53 , MRT63
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
ICC/IF, WB
靶标/特异性:
It is specific for CaMKII alpha pThr286 and does not cross react with CaMKII alpha, CAMK2B, CAMK2B pThr287, CAMK2G, and CAMK2G pThr287.
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide surrounding phospho Thr286 of human CaMKII alpha. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL3570
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018]
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