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折扣/货期| 货号：SIH-242-1G | 规格：1 g | 目录价：￥4132.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Camptothecin
别名:
(4S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
产品描述:
Topoisomerase I inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
348.36
产品形式:
Yellow solid
产地:
加拿大
功能与背景:
Camptothecin is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I. It binds to the topo I and DNA complex, resulting in a tertiary comlex which stabilizes it. This prevents re-ligation and therefore causes DNA damage which results in apoptosis (1-3). It has showed remarkable anti-cancer activity in clinical trials.
纯度:
>98%
来源:
Synthetic
CAS号:
7689-03-4
分子式:
C20H16N2O4
溶解度:
Soluble to 5 mM in DMSO
PubChem CID:
24360
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