| 货号:GTX85405 | 规格:100μg | 目录价:¥6200 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CAPS2 antibody
别名:
calcium dependent secretion activator 2 , CAPS2
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ELISA, IHC-P, WB
靶标/特异性:
Multiple isoforms of CAPS2 are known to exist. This CAPS2 antibody is predicted to be specific to CAPS2 and not recognize CAPS1.
同种型:
IgG
免疫原:
CAPS2 antibody was raised against a 19 amino acid synthetic peptide near the center of the human CAPS2.The immunogen is located within amino acids 510 - 560 of CAPS2.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
148
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
CAPS2 and the related protein CAPS1 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. Like CAPS1, numerous isoforms of CAPS2 are known to exist. These isoforms show distinct expression patterns in the brain. For example, CAPS2b showed high expression in the developing cerebellum. Furthermore, one version of CAPS2 mRNA that lacks exon 3 is detected in some autistic patients, suggesting that the differential expression pattern of CAPS2 is involved in neuronal development. This CAPS2 antibody is predicted to be specific to CAPS2 and not recognize CAPS1.
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