Carbamoyl phosphate synthetase 1 Antibody / CPS1-单抗-深圳欣博盛生物科技有限公司

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Carbamoyl phosphate synthetase 1 Antibody / CPS1

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V5679SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

Carbamoyl phosphate synthetase 1 Antibody / CPS1

产品描述:

This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P, WB

同种型:

Mouse IgG, kappa

免疫原:

A portion of amino acids 800-1000 from human CPS1 protein was used as the immunogen for the Carbamoyl phosphate synthetase 1 antibody.

克隆性:

Monoclonal (mouse origin)