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折扣/货期| 货号：V5244SAF-100UG | 规格：100 ug | 目录价：￥6652.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Carbonic Anhydrase VIII Antibody / CA8
产品描述:
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology, such as ataxia, mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally, it is upregulated in various cancers.
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P,WB
同种型:
Mouse IgG2a, kappa
免疫原:
Recombinant full-length human protein was used as the immunogen for the Carbonic Anhydrase VIII antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
CA8/6814
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the Carbonic Anhydrase VIII antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
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