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折扣/货期| 货号：GTX38839 | 规格：500μg | 目录价：￥5500 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Cardiac Troponin I antibody [4C2]
别名:
troponin I3, cardiac type , CMD1FF , CMD2A , CMH7 , RCM1 , TNNC1 , cTnI
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, Immunoassay, Purification, WB
靶标/特异性:
Reacts equally with free cardiac troponin I (cTnI) and cTnI forming complexes with other troponincomponents. Not affected by heparin, phosphorylation, oxidation and troponin complex formation.Recognizes an epitope located between amino acid residues 23 and 29 of cTnI. No cross-reactivity withskeletal muscle troponin I. Reactive with cTnI from human, bovine, porcine, goat, canine, rabbit, feline, ratand mouse. Not reactive with cTnI from fish.
同种型:
IgG2a
免疫原:
Native troponin complex.
克隆性:
Monoclonal
克隆号:
4C2
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
9.10 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
预期分子量:
24
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
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