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折扣/货期| 货号：1128-0.02 mg | 规格：0.02 mg | 目录价：￥1345.5 |
| 货号：1128-0.1 mg | 规格：0.1 mg | 目录价：￥6084 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Caspase-10 Antibody
别名:
Caspase-10 Antibody: MCH4, Caspase-10, Apoptotic protease Mch-4, CASP-10
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA,WB,IF,ICC
靶标/特异性:
Antibody only recognizes FLICE2 form of caspase-10.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Caspase-10 Antibody is DEAE purified.
偶联:
Unconjugated
产品浓度:
1 mg/ml
保存温度:
Caspase-10 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Caspase-10 Antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
Caspase-10 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. A novel ICE/CED-3 protease was identified recently, designated FLICE2 and Mch4 and renamed as caspase-10. Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors. Caspase-10 is therefore involved in the CD95 and TNFR1 induced apoptosis. Caspase-10 cleaves and activates caspase-3, -4, -6, -7, -8 and -9, which causes the proteolytic cleavage of many key proteins such as PARP. Cleavage of PARP occurs in many different systems during apoptosis and is the hallmark of programmed cell death. Caspase-10 is expressed in many tissues and cell lines.
Accession #:
AAD28402
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