官网链接
折扣/货期| 货号：GTX28377 | 规格：50μg | 目录价：￥2400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Caspase 10 peptide
别名:
Caspase 10 , Alps2 , Flice2 , Mch4 , Casp10
实验应用:
Neutralizing/Inhibition
克隆号:
偶联:
Unconjugated
产品浓度:
0.20 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store the peptide at -20ºC, stable for one year.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
PBS, 0.1% BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Caspases are a family of intracellular proteases that mediate cell death and are the principal effectors of apoptosis. Caspase 10 (Mch4, ICE-LAP4, FLICE2) plays an important role in apoptosis induced by a variety of inducers such as TNF alpha and Anti-Fas antibody. It is a large prodomain caspase classified together with caspases 2, 8, and 9 as a signaling caspase. Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) having the same prodomain but different mature large and small subdomain, have been described. Caspase 10 contains two death domains (DED) involved in linking to the death effector domain of the adapter protein FADD and recruiting the complex to TNFR1 and Fas. The inactive procaspase 10 is variably expressed in many tissues and cell lines as a cytosolic protein. The mature form of caspase 10 comprises two subunits, p23/p17 (splice isoforms) and p12. Interestingly, a caspase 9- dependent processing of caspase 10 by caspase 6 in cell-free extracts has recently been suggested. Caspase 10 can cleave and activate caspases 3, 4, 6, 7, 8, and 9. This is followed by cleavage of numerous key proteins, including the nuclear protein PARP.
您可能感兴趣的产品
In vivo Collagen Hybridizing Peptide, sulfo-Cy7.5 Conjugate
货号：INVIVOKIT7.5
In vivo Collagen Hybridizing Peptide, sulfo-Cy7.5 Conjugate
货号：INVIVOCTL7.5
In vivo Collagen Hybridizing Peptide, sulfo-Cy7.5 Conjugate
货号：INVIVOTGT7.5
Collagen Hybridizing Peptide, Cy3 Conjugate
货号：RED60CTL
Collagen Hybridizing Peptide, Cy3 Conjugate
货号：RED60
Collagen Hybridizing Peptide, Cy3 Conjugate
货号：RED300
Collagen Hybridizing Peptide, Biotin Conjugate
货号：BIO60CTL
Collagen Hybridizing Peptide, Biotin Conjugate
货号：BIO60
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询