Cathepsin C (cleaved Arg394) antibody-多抗-深圳欣博盛生物科技有限公司

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Cathepsin C (cleaved Arg394) antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX86919

规格：100μg

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Cathepsin C (cleaved Arg394) antibody

别名:

CPPI , CTSC , DPP1 , DPPI , HMS , JP , JPD , PALS , PDON1 , PLS , cathepsin C , Cathepsin C

反应种属:

Human

宿主来源:

Rabbit

实验应用:

靶标/特异性:

Cathepsin C (cleaved Arg394) antibody detects endogenous levels of fragment of activated cathepsin C resulting from cleavage adjacent to Arg394.

同种型:

IgG

免疫原:

The antiserum was produced against synthesized peptide derived from human Cathepsin C (345-394).

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. [provided by RefSeq, Nov 2015]

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