深圳欣博盛生物科技有限公司 a1

货号:GTX53915 规格:100μl 目录价:¥5000
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Cbl-b antibody
别名:
Cbl proto-oncogene B , Cbl-b , Nbla00127 , RNF56
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human CBLB (NP_733762.2).
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
109
产品形式:
Liquid
存储溶液:
PBS, 50% Glycerol, 0.05% ProClin 300.
生产商:
GeneTex
功能与背景:
This gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell receptor, and high affinity immunoglobulin epsilon receptor activation. Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and infections. [provided by RefSeq, Sep 2017]
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