官网链接
折扣/货期| 货号：GTX639943 | 规格：500μl | 目录价：￥6500 |
| 货号：GTX639943-S | 规格：100μl | 目录价：￥3300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CBP antibody [HMV319] HistoMAX™
别名:
CREB binding protein,CBP,KAT3A,MKHK1,RSTS,RSTS1
产品描述:
This antibody was validated on 76 different Normal Tissues by IHC-P.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
靶标/特异性:
<b>Highly recommended for IHC-P in human tissues.</b>
同种型:
IgG
免疫原:
Recombinant fragmemt of human CBP
克隆性:
Monoclonal
克隆号:
HMV319
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
0.44 mg/ml
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 2% BSA, 0.025% ProClin 300.
生产商:
GeneTex
功能与背景:
This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
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