CCR1 antibody-多抗-深圳欣博盛生物科技有限公司

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CCR1 antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX13240

规格：50μg

目录价：￥4700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CCR1 antibody

别名:

CC motif chemokine receptor 1,CCR1,CD191,CKR1,CMKBR1,HM145,MIP1aR,SCYAR1,C-C motif chemokine receptor 1

反应种属:

Human

宿主来源:

Goat

实验应用:

ELISA, FCM, IHC, WB

靶标/特异性:

Peptide sequence is < 50 % identical to other chemokine receptors in this region.

同种型:

IgG

免疫原:

Synthetic peptide TEDYDTTTEFDYGDATPC corresponding to amino acids 7-24 of the N-terminal extracellular domain of human CCR1

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

10mM KHPO₄, 140mM NaCl, 0.1% BSA, 0.1% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]

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