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折扣/货期| 货号：GTX11466 | 规格：50μg | 目录价：￥3900 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CCR5 antibody [HEK/1/85a] (FITC)
别名:
C-C motif chemokine receptor 5 (gene/pseudogene) , CC-CKR-5 , CCCKR5 , CCR-5 , CD195 , CKR-5 , CKR5 , CMKBR5 , IDDM22
反应种属:
Human, Mouse
宿主来源:
Rat
实验应用:
FCM
同种型:
IgG2a
免疫原:
CHO cells transfected with human CCR5.
克隆性:
Monoclonal
克隆号:
HEK/1/85a
纯化方式:
Protein G purified
偶联:
FITC
产品浓度:
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2015]
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