| 货号:GTX640521-S | 规格:25μl | 目录价:¥1700 |
| 货号:GTX640521 | 规格:100μl | 目录价:¥4000 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CCR7 antibody [HL3075]
别名:
C-C motif chemokine receptor 7 , BLR2 , CC-CKR-7 , CCR-7 , CD197 , CDw197 , CMKBR7 , EBI1
反应种属:
Human, Rat
宿主来源:
Rabbit
实验应用:
IHC-P
靶标/特异性:
This antibody is specific for human CCR7 protein and does not cross react with human CCR1, CCR2, CCR4, CCR5, CCR9, and CCR10 protein.<br>This antibody was raised against human CCR7 Extracellular domain.
同种型:
IgG
免疫原:
Synthetic peptide encompassing a sequence within the Extracellular domain of human CCR7. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL3075
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
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