深圳欣博盛生物科技有限公司 a1

CCT241736
货号:26185-10 mg 规格:10 mg 目录价:¥1903
货号:26185-25 mg 规格:25 mg 目录价:¥4395
货号:26185-5 mg 规格:5 mg 目录价:¥1206
货号:26185-50 mg 规格:50 mg 目录价:¥8161
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CCT241736
产品描述:
A dual inhibitor of Aurora kinase (Kds = 7.5 and 48 nM for Aurora A and B, respectively) and FLT3 (Kds = 6.2, 38, and 14 nM for wild-type, FLT3ITD, and FLT3D835Y, respectively); inhibits the activity of 22 additional kinases by >90% in a panel of 386 nonmutant kinases at 1 µM; inhibits cell growth of SW620, HCT116, MOLM-13, and MV4-11 cancer cells (GI50s = 1, 0.3, 0.1, and 0.3 µM, respectively); oral administration reduces tumor growth by 58% in an MV4-11 mouse xenograft model at 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
456.3706
产品形式:
A crystalline solid
纯度:
≥90%
CAS号:
1402709-93-6
分子式:
C22H23Cl2N7
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