深圳欣博盛生物科技有限公司 a1

CD13 Antibody / ANPEP
货号:RQ7957 规格:100 ug 目录价:¥6488.05
产品详情
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产品名称:
CD13 Antibody / ANPEP
产品描述:
Membrane alanyl aminopeptidase (EC 3.4.11.2) also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N) is an enzyme that in humans is encoded by the ANPEP gene. It is mapped to 15q26.1. Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
反应种属:
Human, Rat, Monkey
宿主来源:
Mouse
实验应用:
WB, IHC-P
同种型:
Mouse IgG1
免疫原:
E. coli-derived recombinant human protein (amino acids D148-S966) was used as the immunogen for the CD13 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
7F2
纯化方式:
Antigen affinity purified
保存温度:
After reconstitution, the CD13 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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