| 货号:V4012-100UG | 规格:100 ug | 目录价:¥6652.1 |
| 货号:V4012-20UG | 规格:20 ug | 目录价:¥3082.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD13 Antibody / ANPEP
产品描述:
Recognizes an integral membrane glycoprotein of 150kDa, identified as CD13 (also known as aminopeptidase-N). The CD13 antigen is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemias. CD13 is absent from normal lymphocytes, platelets and erythrocytes. CD13 is also present on fibroblasts, endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. CD13 is identical to aminopeptidase N (APN), a prominent membrane-bound metalloprotease present on the surface of intestinal brush border and renal tubules. CD13 plays a role in metabolism of biologically active peptides, in phagocytosis, and in bactericidal / tumoricidal activities. It also serves as a receptor for human coronaviruses (HCV). The lineage-restricted pattern of expression of CD13 within the hemopoietic compartment suggests that it may be important in myeloid cell differentiation.
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, WB, IHC-P
同种型:
Mouse IgG2b, kappa
免疫原:
A portion of amino acids 50-250 from the human ANPEP protein was used as the immunogen for the CD13 antibody. The antibody recognizes an extracellular epitope.
克隆性:
Monoclonal (mouse origin)
克隆号:
APN/6997
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the CD13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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