CD161 antibody [HP-3G10]-单抗-深圳欣博盛生物科技有限公司

首页产品中心单抗

CD161 antibody [HP-3G10]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX01454

规格：100μg

目录价：￥1800

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CD161 antibody [HP-3G10]

别名:

killer cell lectin like receptor B1 , CD161 , CLEC5B , KLRB1 , NKR , NKRP1 , NKRP1A , hNKRP1A

产品描述:

The HP-3G10 antibody is specific for human CD161, also known as NKR-P1A, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. CD161 exists as a homodimer which is prominently expressed on natural killer (NK) and NKT cells, where it is proposed to regulate the function of both cell types. CD161 is also found on T cell subsets, including T regulatory cells (Tregs), memory/effector CD4+ T cells, and CD8+ T cells. Th17 cells have been demonstrated to co-express CD161, as surface IL-17A+ cells are contained within the CD161+ fraction of CD4 T cells, so that CD161 (in combination with CCR6) is often used as a marker for enrichment of Th17 cells.The HP-3G10 antibody may be used for flow cytometric analysis of CD161 on NK and NKT cells, as well as on various T cell subsets. The antibody is also reported to be cross-reactive with Baboon, Chimpanzee and Rhesus CD161.

反应种属:

Baboon, Chimpanzee, Human, Rhesus Monkey

宿主来源:

Mouse

实验应用:

Depletion, FCM, WB

同种型:

IgG1

克隆性:

Monoclonal

克隆号:

HP-3G10

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

10mM NaH₂PO₄, 150mM NaCl, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]

您可能感兴趣的产品

Chk1 (phospho Ser317) antibody [HL4313]

货号：GTX643560

SLC25A1 antibody [HL4228]

货号：GTX643061

Latrophilin 2 antibody [HL4090]

货号：GTX642529

PSD93 antibody [GT126]

货号：GTX642326

PRRS virus Nucleocapsid protein antibody [GT119]

货号：GTX642224

CXCL10 / IP10 antibody [HL3871]