| 货号:CHI-MF-120CD200-C050 | 规格:50 ug | 目录价:¥4620 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD200 (mouse):Fc (mouse) (rec.) (non-lytic)
别名:
OX-2 Membrane Glycoprotein; MOX2
产品描述:
CD200, also known as OX-2, is a 45 kDa transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD200. CD200 knockout mice are characterized by increased macrophage number and activation and are predisposed to autoimmune disorders. In T cells, CD200 functions as a costimulatory molecule independent of the CD28 pathway. Several viruses encode CD200 homologs which are expressed on infected cells during the lytic phase. Like CD200 itself, viral CD200 homologs also suppress myeloid cell activity, enabling increased viral propagation.
宿主来源:
CHO cells
保存温度:
+4°C
运输温度:
BI
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
Shows the biological function of the CD200 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
内毒素水平:
<0.06EU/µg protein (LAL test; Lonza).
上一个:CD276 [B7-H3] (mouse):Fc (mouse) (rec.) (non-lytic)
下一个:CD54 [ICAM-1] (mouse):Fc (mouse) (rec.) (non-lytic)
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