CD206 Antibody / Macrophage mannose receptor 1 / MRC1-单抗-深圳欣博盛生物科技有限公司

首页产品中心单抗

CD206 Antibody / Macrophage mannose receptor 1 / MRC1

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V5766SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CD206 Antibody / Macrophage mannose receptor 1 / MRC1

产品描述:

CD206, also known as macrophage mannose receptor type C (MMR, MRC1L1 and MRC1), is a type I membrane receptor protein. It is an phagocytic and endocytic receptor that can recognize carbohydrate ligands in target molecules. The extracellular portion of the protein includes eight C-type carbohydrate recognition domains (CRD) which are clustered together to achieve higher affinity binding to saccharides. CD206 is found on macrophages and on endothelial cells of the liver and is the only known example of a C-type lectin that contains multiple C-type CRDs. CD206 mediates the endocytosis of glycoproteins by macrophages and binds high-mannose structures on the surface of potentially pathogenic viruses, fungi and bacteria enabling them to be neutralized by phagocytic engulfment. During inflammation, CD206 is crucial for rapid clearance of several mannose-bearing serum glycoproteins but does not regulate the initiation of inflammation. CD206 is primarily expressed in mature tissue macrophages and immature dendritic cells, as well as hepatic and lymphatic endothelial cells, retinal pigmental epithelium (RPE) and mesangial cells.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG2c, kappa

免疫原:

A portion of amino acids 1100-1400 from human Macrophage mannose receptor 1 protein was used as the immunogen for the CD206 antibody.

克隆性:

Monoclonal (mouse origin)