CD273 [PD-L2] (human):Fc (mouse) (rec.)-Fc融合蛋白-深圳欣博盛生物科技有限公司

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CD273 [PD-L2] (human):Fc (mouse) (rec.)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CHI-HF-211PDL2-C100

规格：100 ug

目录价：￥5040

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CD273 [PD-L2] (human):Fc (mouse) (rec.)

别名:

Programmed Cell Death 1 Ligand 2; PDCD1 Ligand 2; B7-DC; PDL2

产品描述:

T cells require a signal induced by the engagement of the T cell receptor and a costimulatory signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273 (PD-L2) is one of two ligands for programmed death-1 (PD-1; CD279), a member of the CD28 family of immunoreceptors. The other identified ligand is PD-L1. CD273 is broadly expressed and also up regulated in a variety of tumor cell lines. On previously activated T cells, CD273 interaction with PD-1 inhibits TCR mediated proliferation and cytokine production, suggesting an inhibitory role in regulating immune responses. CD273 has a costimulatory function on resting T cells activated with suboptimal TCR signals.

宿主来源:

CHO cells

保存温度:

+4°C

运输温度:

产品形式:

solid

存储溶液:

Lyophilized from 0.2µm-filtered solution in PBS.

有效期:

Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

产地: