CD275 [B7-H2] (mouse):Fc (mouse) (rec.) (non-lytic)-Fc融合蛋白-深圳欣博盛生物科技有限公司

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CD275 [B7-H2] (mouse):Fc (mouse) (rec.) (non-lytic)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CHI-MF-120B7H2-C100

规格：100 ug

目录价：￥5180

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CD275 [B7-H2] (mouse):Fc (mouse) (rec.) (non-lytic)

别名:

B7-H2; ICOS Ligand; B7-like Protein Gl50; B7RP-1

产品描述:

Mouse CD275 (B7-H2) is a member of the growing B7 family of immune costimulatory proteins. CD275 has been identified as the ligand for ICOS, a member of the CD28 family of co-stimulatory receptors. Mouse CD275 is expressed on resting B cells and at low levels on monocytes. The CD275/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.

宿主来源:

CHO cells

靶标/特异性:

Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement (C1q) and FcgammaR I binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).

保存温度:

+4°C

运输温度:

产品形式:

solid

存储溶液:

Lyophilized from 0.2µm-filtered solution in PBS.

产地:

瑞士

纯度:

>98% (SDS-PAGE)

生物活性:

Measured by its binding ability in a functional ELISA. Immobilized human ICOS at 1µg/ml (100µl/well) can bind biotinylated B7-H2 (mouse):Fc (mouse) (rec.) (non-lytic) with a linear range of 0.1-1.0µg/ml. Optimal dilutions should be determined by each laboratory for each application.

内毒素水平:

<0.06EU/µg protein (LAL test; Lonza).

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