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折扣/货期| 货号：GTX42110 | 规格：25μg | 目录价：￥2900 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD3 epsilon antibody [CD3-12]
别名:
CD3e molecule , IMD18 , T3E , TCRE
反应种属:
Alpaca, Amazon Parrot, Bovine, Bullfrog, Cat, Chicken, Cynomolgus monkey, Dog, Duck, Great horned owl (Bubo virginianus), Harbour Porpoise, Horse, Human, Koala, Mouse, Pig, Rabbit, Raccoon, Rhesus Monkey, Sea Lion, Spotted Hyena, Xenopus
宿主来源:
Rat
实验应用:
FCM, ICC/IF, IHC-Fr, IHC-P, WB
靶标/特异性:
This antibody has been specifically raised against an epitope within the epsilon peptide chain, highly conserved among species clone CD3-12 has a very broad species crossreactivity for the CD3 marker.
同种型:
IgG1
免疫原:
Synthetic peptide sequence derived from cytoplasmic epitope of CD3 (Glu-Arg-Pro-Pro-Pro-Val-Pro-Asn-Pro-Asp-Tyr-Glu-Pro-Cys) (ERPPPVPNPDYEPC)
克隆性:
Monoclonal
克隆号:
CD3-12
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
23
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
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