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折扣/货期| 货号：AG-40B-0083-3050 | 规格：3 x 50 ug | 目录价：￥6000 |
| 货号：AG-40B-0083-C050 | 规格：50 ug | 目录价：￥3000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD40 (human):Fc (human) (rec.)
别名:
Tumor Necrosis Factor Receptor Superfamily Member 5; TNFRSF5; CD40L Receptor
产品描述:
CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.
宿主来源:
HEK 293 cells
靶标/特异性:
Binds human and mouse CD40L.
产品浓度:
1mg/ml after reconstitution
保存温度:
+4°C
运输温度:
BI
预期分子量:
~54kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
生物活性:
Blocks the binding of CD40L to CD40.
内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
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