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折扣/货期| 货号：CHI-HF-211CD45-C050 | 规格：50 ug | 目录价：￥4620 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD45 (human):Fc (mouse) (rec.)
别名:
LCA; LY5; B220; T200; CD45R; GP180; PTPRC
产品描述:
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. CD45 is found expression specifically in hemotopietic cells. CD45 consists of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. It serves as an essential regulator of T-cell and B-cell antigen receptor signaling through either direct interaction with components of the antigen receptor complexs or by activating various Src family kinases required for the antigen receptor signaling and it also can suppress JAK kinases.
宿主来源:
HEK 293 cells
保存温度:
+4°C
运输温度:
BI
预期分子量:
~65kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
Measured by its binding ability in a functional ELISA assay.
内毒素水平:
<5EU/mg protein (LAL test; Lonza).
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