CD46 antibody [MEM-258] (PE)-单抗-深圳欣博盛生物科技有限公司

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CD46 antibody [MEM-258] (PE)

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX78353

规格：100test

目录价：￥4400

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CD46 antibody [MEM-258] (PE)

别名:

AHUS2 , CD46 , CD46 molecule , MCP , MIC10 , TLX , TRA2.10

反应种属:

Bovine, Human

宿主来源:

Mouse

实验应用:

FCM

靶标/特异性:

This antibody recognizes an epitope on SCR4 (the membrane-proximal SCR) domain of CD46 (Membrane cofactor protein).

同种型:

IgG1

免疫原:

HPB-ALL human T cell line

克隆性:

Monoclonal

克隆号:

MEM-258

纯化方式:

Purified by size-exclusion chromatography

偶联:

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 15mM Sodium azide.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]

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