深圳欣博盛生物科技有限公司 a1

CD5 Antibody [CD5/54/F6]
品牌:ProSci LLC
货号:33-550 规格:100 ug 目录价:¥10986.3
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD5 Antibody [CD5/54/F6]
别名:
T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, CD5, CD5, LEU1
反应种属:
Human,Monkey,Horse,Pig,Rabbit,Bovine,Rat,Guinea Pig,Chicken
宿主来源:
Mouse
实验应用:
WB,Flow,IF,IHC
同种型:
IgG1, kappa
克隆性:
Monoclonal
克隆号:
CD5/54/F6
纯化方式:
Protein G affinity chromatography
偶联:
Unconjugated
产品浓度:
0.2 mg/mL
保存温度:
Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
产地:
美国
生产商:
Prosci
功能与背景:
Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
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