| 货号:V4722SAF-100UG | 规格:100 ug | 目录价:¥6652.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CD64 Antibody / FCGR1A
产品描述:
Three different classes of IgG Fc receptors have been described: Fc gamma RI (CD64), Fc gamma RII (CD32) and Fc gamma RIII (CD16). The low affinity receptors, CD64 and CD16, have a putative role in mediating humoral immune responses. CD64 is a surface glycoprotein with high affinity for monomeric IgG, is expressed constitutively on monocytes and macrophages, and can be induced in neutrophils subsequent to IFN-gamma stimulation. CD64 plays a putative role in the initiation of cell-mediated cytotoxicity. Thus far, three genes encoding four distinct CD64 transcripts have been described. CD64 has been shown to associate with signal transducing subunit of the high affinity IgE receptor. Src family kinases Hck and Lyn show increased kinase activity and will coimmunoprecipitate with CD64 subsequent to receptor cross linking.
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
同种型:
Mouse IgG
免疫原:
A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the CD64 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
FCGR1A/7496
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the CD64 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
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