CD66a Antibody / CEACAM1 / BGP-1-单抗-深圳欣博盛生物科技有限公司

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CD66a Antibody / CEACAM1 / BGP-1

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V5793SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

CD66a Antibody / CEACAM1 / BGP-1

产品描述:

Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constantlike A and/or B domains. CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1), also known as BGP or BGP1, is a 526 amino acid protein that exists as seven alternatively spliced isoforms, some of which localize to the cell membranes, while others are secreted. One of several members of the CEACAM family, CEACAM1 contains one Ig-like V-type domain and three Ig-like C2-type domains and is thought to play a role in a variety of cellular activities, including angiogenesis, apoptosis, arrangement of tissue threedimensional structure and modulation of innate and adaptive immune responses. Additionally, CEACAM1 is underexpressed in colorectal cancers, suggesting a role in tumor suppression.

反应种属:

Human

宿主来源:

Mouse

实验应用:

WB, IHC-P

同种型:

Mouse IgG1, kappa

免疫原:

A portion of amino acids 50-250 from human CEACAM1 protein was used as the immunogen for the CD66a antibody.

克隆性:

Monoclonal (mouse origin)