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折扣/货期| 货号：GTX44154 | 规格：500μg | 目录价：￥5600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CEACAM1 antibody [B464M]
别名:
carcinoembryonic antigen related cell adhesion molecule 1 , BGP , BGP1 , BGPI
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, IHC, Sandwich ELISA
靶标/特异性:
Does not crossreact with human leukocytes in cytofluorometry.Staining in immunohistochemistry:Brightness 80 Cytoplasmic Staining 3+ Membrane Staining 2+ Background 2+ Staining of Mucus 2+
同种型:
IgG1
免疫原:
Human natural tumor-derived purified CEA antigen.
克隆性:
Monoclonal
克隆号:
B464M
纯化方式:
Purified by Ion Exchange Chromatography
偶联:
Unconjugated
产品浓度:
5.10 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
10mM Tris, 150mM NaCl, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010]
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