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折扣/货期| 货号：60-497 | 规格：400 ul | 目录价：￥9108.45 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Cellular Apoptosis Susceptibility Antibody
别名:
Exportin-2, Exp2, Cellular apoptosis susceptibility protein, Chromosome segregation 1-like protein, Importin-alpha re-exporter, CSE1L, CAS, XPO2
反应种属:
Human,Mouse
宿主来源:
Rabbit
实验应用:
WB,IHC-P,IF
同种型:
Rabbit Ig
克隆性:
Polyclonal
纯化方式:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Supplied in PBS with 0.09% (W/V) sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, CSE1L may play a role both in apoptosis and in cell proliferation.
Accession #:
P55060
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