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折扣/货期| 货号：SMC-202D-PCP | 规格：100 µg | 目录价：￥4599 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CENP-A Antibody: PerCP
别名:
CENP A Antibody, cenpa Antibody, Centromere auto antigen A Antibody, Histone H3 like centromeric protein A Antibody
产品描述:
Mouse Anti-Human CENP-A Monoclonal IgG1
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB | ICC/IF
靶标/特异性:
Detects ~18kDa. Recognizes Human CENP-A.
同种型:
IgG1
推荐稀释度:
WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
免疫原:
Synthetic peptide corresponding to a portion of human CENP-A
免疫原种属:
Human
克隆性:
Monoclonal
克隆号:
5A7-2E11
纯化方式:
Protein G Purified
偶联:
PerCP
产品浓度:
1 mg/ml
保存温度:
Conjugated antibodies should be stored according to the product label
运输温度:
Blue Ice or 4ºC
存储溶液:
PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
产地:
加拿大
功能与背景:
A replicated chromosome includes two kinetochores that control chromosome segregation during mitosis. The Centromere Protein-A, CENP-A, is a Histone H3-like protein that contains a C-terminal H3-like domain, which is required for centromere localization of CENP-A, and an antigenic N-terminal domain. CENP-A, originally isolated from HeLa cells, is essential for kinetochore targeting of CENP-C. In the presence of DNA CENP-A forms an octa-meric complex with histones H4, H2A, H2B. CENP-A specifically localizes to active centromeres and is a component of specialized centromeric nucleosomes, on which kinetochores are assembled. CENP-A is essential for nucleosomal packaging of centromeric DNA at interphase and functions as a centromere formation marker on the chromosome.
Accession #:
NP_001035891.1
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