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折扣/货期| 货号：7133-0.02 mg | 规格：0.02 mg | 目录价：￥1345.5 |
| 货号：7133-0.1 mg | 规格：0.1 mg | 目录价：￥6084 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CHCHD6 Antibody
别名:
CHCHD6 Antibody: CHCM1, PPP1R23, CHCM1, Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial, Coiled coil helix cristae morphology protein 1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA,WB
靶标/特异性:
CHCHD6 is predicted to not cross-react to other members of the CHCHD family.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
CHCHD6 Antibody is affinity chromatography purified via peptide column.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
CHCHD6 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
CHCHD6 Antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
CHCHD6 Antibody: CHCHD6 is a member of a family of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain and has been observed in a complex with the mitochondrial proteins mitofilin, SAM50, metaxins 1 and 2, and CHCHD3. CHCHD6 knockdown causes severe defects in mitochondrial cristae morphology as well as reductions in cell growth, ATP production and oxygen consumption. This decrease of CHCHD6 also led to a reduction in mitofilin protein levels, while a knockdown of mitofilin resulted in a reduced level of CHCHD6, suggesting coordinate regulation between these two proteins. CHCHD6 knockdown in human cancer cells enhances their sensitivity to genotoxic anticancer drugs, suggesting that CHCHD6 may be a potential therapeutic anti-tumor target.
Accession #:
NP_115719
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