Chk2 Antibody-多抗-深圳欣博盛生物科技有限公司

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Chk2 Antibody

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：2391-0.02 mg	规格：0.02 mg	目录价：￥1345.5
货号：2391-0.1 mg	规格：0.1 mg	目录价：￥6084

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Chk2 Antibody

别名:

Chk2 Antibody: CDS1, CHK2, LFS2, RAD53, hCds1, HuCds1, PP1425, CDS1, CHK2 checkpoint homolog, Hucds1

反应种属:

Human,Mouse,Rat

宿主来源:

Rabbit

实验应用:

ELISA,WB,ICC,IF

同种型:

IgG

克隆性:

Polyclonal

纯化方式:

Chk2 Antibody is affinity chromatography purified via peptide column.

偶联:

Unconjugated

产品浓度:

1 mg/mL

保存温度:

Chk2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

Chk2 Antibody is supplied in PBS containing 0.02% sodium azide.

产地:

美国

生产商:

Prosci

功能与背景:

Chk2 Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including Chk2, p53R2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. The checkpoint kinase Chk2 is the mammalian homologue of yeast Cds1/Rad53. In response to DNA damage, the checkpoint kinase ATM phosphorylates and activates Chk2, which in turn directly phosphorylates and activates p53. Chk2 serves as ATM downstream effector to mediate activation of p53. Chk2 also phosphorylates and activates BRCA1, the product of a tumor suppressor gene that is mutated in breast and ovarian cancer.

Accession #:

NP_009125

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