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折扣/货期| 货号：AG-CR1-3590-M050 | 规格：50 mg | 目录价：￥360 |
| 货号：AG-CR1-3590-M250 | 规格：250 mg | 目录价：￥1080 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Cisplatin
别名:
cis-Diamminedichloroplatinum (II); Neoplatin; CDDP; cis-DDP; NSC119875; NK 801; TR170
产品描述:
Potent platinum-based antineoplastic agent [1, 10]. Anticancer compound [1]. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death [2, 12, 13, 15]. Nephrotoxic when used in vivo [3]. Potent chemoimmunotherapeutic. Stimulates the immune responses by activating macrophages and other cells of the immune system [4, 6]. Apoptosis inducer via p53-dependent and -independent mechanisms [5, 7, 8]. Induces apoptosis through caspase-3 activation and XIAP expression inhibition [9, 14]. Targets other proteins and enzymes [10]. Non-competitive NHE-1 inhibitor, an archetypal, membrane-bound mechanosensitive sodium-hydrogen ion transporter [16].
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
300
产品形式:
solid
产地:
瑞士
纯度:
>98%
CAS号:
15663-27-1
分子式:
Cl2H6N2Pt
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