3-Methyladenine-抑制剂-深圳欣博盛生物科技有限公司

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3-Methyladenine

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CR1-3597-M025	规格：25 mg	目录价：￥420
货号：AG-CR1-3597-M100	规格：100 mg	目录价：￥1140
货号：AG-CR1-3597-M250	规格：250 mg	目录价：￥2160

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

3-Methyladenine

别名:

3-MA; 3MeA; 6-Amino-3-methylpurine; NSC 66389

产品描述:

Potent cell permeable and selective inhibitor of phosphatidyl-inositol 3-kinase (PI3K) [1, 7, 8]. Blocks class I, class II and class III PI3Ks, including some downstream targets [8]. Blocks class I PI3K persistently and class III PI3K transiently [7]. Induces autophagy under nutrient-rich conditions and inhibits starvation-induced autophagy due to differential effects on class I versus class III PI3 kinase [5, 7]. Shows some limited Vps34 preference in vitro compared to PtdIns3Kgamma. However, it is typically employed in cellular studies at a concentration of 10 mM, which can inhibit all PtdIns3Ks [8]. Can target other kinases and affect other cellular processes, such as glycogen metabolism, lysosomal acidification, endocytosis and mitochondrial permeability transition [2-4]. Anticancer compound [6, 10, 12]. Neuroprotective [9, 11]. PKA-activation dependent lipolytic agent. Enhances ATGL-dependent hydrolysis of triacylglycerols [13].

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

149.2

产品形式:

solid

产地:

瑞士

纯度:

>98%