Claudin 14 blocking peptide-封闭肽-深圳欣博盛生物科技有限公司

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Claudin 14 blocking peptide

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX19035-PEP

规格：100μg

目录价：￥3200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Claudin 14 blocking peptide

别名:

Claudin 14 , Dfnb29 , Cldn14

靶标/特异性:

The peptide was used in the production of GTX19035.

克隆号:

产品浓度:

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Lyophilized powder

存储溶液:

Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.

生产商:

GeneTex

功能与背景:

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [p

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