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折扣/货期| 货号：GTX636283 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX636283-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CLOCK antibody [HL1099]
别名:
clock circadian regulator , KAT13D , bHLHe8
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ICC/IF, IHC-P, WB
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the C-terminus region of human CLOCK. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL1099
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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