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折扣/货期| 货号：30610-1 mg | 规格：1 mg | 目录价：￥549.4 |
| 货号：30610-10 mg | 规格：10 mg | 目录价：￥4180.8 |
| 货号：30610-25 mg | 规格：25 mg | 目录价：￥7812.2 |
| 货号：30610-5 mg | 规格：5 mg | 目录价：￥2492.4 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CNX-2006
产品描述:
An irreversible inhibitor of mutant EGFRs; inhibits EGFR phosphorylation in PC-9 and HCC827 cells (IC50s = 55-104 nM), which express the EGFRDel E746_A750 mutation, and NCI H1975 and PC-9/GR4 cells (IC50s = 46 and 61 nM, respectively), which express the EGFRL858R/T790M and EGFRDel E746_A750/T790M mutations, respectively; >10-fold selective for cells expressing these mutants over A549 cells expressing wild-type EGFR; inhibits growth in a panel of NSCLC cells expressing wild-type or mutant EGFRs (GI50s = 0.34-8 and 0.003-3.6 μM, respectively); reduces tumor growth in an NCI H1975 mouse xenograft model at 25 and 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
545.532172
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1375465-09-0
分子式:
C26H27F4N7O2
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