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折扣/货期| 货号：GTX54647 | 规格：250μg | 目录价：￥8000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
COL17A1 antibody [NC16a-3]
别名:
collagen type XVII alpha 1 chain , BA16H23.2 , BP180 , BPA-2 , BPAG2 , ERED , LAD-1
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, IHC-Fr, IHC-P, WB
靶标/特异性:
This antibody recognizes the NC16a-domain of collagen XVII (aa 545-557). It does not cross-react with mouse and rat skin based on internal testing; other species not tested.
同种型:
IgG1
免疫原:
Purified recombinant NC16a-domain of collagen XVII. The epitope has been mapped to aa545-557 (PMID: 19158842).
克隆性:
Monoclonal
克隆号:
NC16a-3
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
150
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]
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