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折扣/货期| 货号：GTX636771 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX636771-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
COL4A1 antibody [HL1351]
别名:
collagen type IV alpha 1 chain , BSVD , RATOR
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
ICC/IF, IHC-P, WB
靶标/特异性:
This antibody may not be suitable for mouse WB assay, as its mouse reactivity is based on IHC-P testing.
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the N-terminus of human COL4A1. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL1351
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
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