Collagen I antibody (Biotin)-多抗-深圳欣博盛生物科技有限公司

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Collagen I antibody (Biotin)

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX26577

规格：50μg

目录价：￥5900

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Collagen I antibody (Biotin)

别名:

collagen type I alpha 1 chain , EDSARTH1 , EDSC , OI1 , OI2 , OI3 , OI4

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

Dot, FCM, ICC/IF, IHC-P, Multiplexing, WB

靶标/特异性:

Some class-specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues. This antibody reacts with most mammalian Type I collagens and has expected cross-reactivity with Type III and negligible cross reactivity with Type II, IV, V or VI collagens.

同种型:

IgG

免疫原:

Collagen Type I from human and bovine placenta.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Biotin

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

20mM Potassium Phosphate, 150mM NaCl, 1% BSA, 0.01% Sodium azide.

生产商:

GeneTex

功能与背景:

This antibody is well suited to detect extracellular matrix proteins in normal as well as disease state tissues. Disruption of tissue organization is the hallmark of neoplasia. Malignant lesions can be distinguished from benign by examining the breakdown of basement membranes and loss of 3-dimensional architecture. Malignant cells are presumed to use matrix metalloproteases to degrade barriers created by the extracellular matrix, which then allows metastasis to occur. Collagenases, stomelysins and gelatinases can collectively degrade all of the various components of the extracellular matrix, including fibrillar and non-fibrillar collagens and basement membrane glycoproteins.

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