Collagen I antibody [COL-1]-单抗-深圳欣博盛生物科技有限公司

首页产品中心单抗

Collagen I antibody [COL-1]

买大送小新年开门红～买大送小，好礼四选一！

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX26308

规格：100μl

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Collagen I antibody [COL-1]

别名:

collagen type I alpha 1 chain

产品描述:

Collagen I antibody (Collagen 1 antibody) detects type I collagen, a fibrillar type collagen found in almost all connective tissues. The main isoform of type I collagen is a heterotrimer of two α1 and one α2 chains subject to significant posttranslational modification and crosslinking. Mutations in type I collagen are found in osteogenesis imperfecta and Ehlers-Danlos syndrome, but this collagen is also linked to other connective tissue disease as well as disorders associated with aging.

反应种属:

Bovine, Deer, Human, Mouse, Pig, Rabbit, Rat

宿主来源:

Mouse

实验应用:

Dot, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB

靶标/特异性:

The antibody is reactive with the native (helical) form of collagen type I in ELISA and dot blot. The product is not reactive when tested on thermally denatured molecules. In immunohistochemical staining of acetone-fixed and unfixed frozen sections, a strong staining of connective tissue fibers is seen. Using the dot blot and ELISA techniques, the antibody shows no cross-reactivity with collagen types, II, III, IV, V, VI, VII, IX, X and XI. The epitope recognized by the antibody is sensitive to routine formalin fixation and paraffin embedding.

同种型:

IgG1

免疫原:

bovine skin collagen type I

克隆性:

Monoclonal

克隆号:

COL-1

纯化方式:

Unpurified

偶联:

Unconjugated

产品浓度:

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

139

产品形式:

Liquid

存储溶液:

Ascites, 15mM Sodium azide.

生产商:

GeneTex

功能与背景:

Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.

您可能感兴趣的产品

Sialosyl-Tn antigen antibody (Prediluted for IHC)

货号：75R-1060

Insulin antibody (Prediluted for IHC)

货号：75R-1058

MPO antibody (Prediluted for IHC)

货号：75R-1050

Luteinizing Hormone antibody (Prediluted for IHC)

货号：75R-1049

Desmin antibody (Prediluted for IHC)

货号：75R-1048

Transferrin antibody (Prediluted for IHC)