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折扣/货期| 货号：27669-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：27669-10 mg | 规格：10 mg | 目录价：￥3591 |
| 货号：27669-5 mg | 规格：5 mg | 目录价：￥2050 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CP 99,994 (hydrochloride)
产品描述:
A nonpeptide NK1 receptor antagonist (Ki = 0.25 nM in a radioligand binding assay); selective for NK1 over NK2 and NK3 receptors (Kis = >10 μM for both); inhibits excitation of guinea pig locus coeruleus cells induced by substance P in vitro (IC50 = 25 nM); inhibits increases in horizontal locomotor activity induced by [Sar9,Met(O2)11]-substance P in guinea pigs (ID50 = 0.59 mg/kg); inhibits aerosolized capsaicin-induced plasma extravasation in guinea pig lung (ID50 = 4 mg/kg); exhibits anti-emetic effects in ferret models of emesis induced by copper sulfate, loperamide, or cisplatin at 0.3 and 1 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
296.40674
产品形式:
A solid
纯度:
≥98%
CAS号:
145148-39-6
分子式:
C19H24N2O • 2HCl
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