CPS1 Antibody / Carbamoyl phosphate synthetase 1-单抗-深圳欣博盛生物科技有限公司

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CPS1 Antibody / Carbamoyl phosphate synthetase 1

品牌：NSJ Bio

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说明书

折扣/货期

货号：V5676-100UG	规格：100 ug	目录价：￥6652.1
货号：V5676-20UG	规格：20 ug	目录价：￥3082.1

产品详情

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产品名称:

CPS1 Antibody / Carbamoyl phosphate synthetase 1

产品描述:

This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG1, kappa

免疫原:

A recombinant human CPS1 protein was used as the immunogen for the CPS1 antibody.

克隆性:

Monoclonal (mouse origin)