官网链接
折扣/货期| 货号：CDX-C0699-M010 | 规格：10 mg | 目录价：￥1414 |
| 货号：CDX-C0699-M050 | 规格：50 mg | 目录价：￥4270 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Crizotinib
别名:
(R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine; PF 2341066; PF-02341066; PF02341066; Xalkori
产品描述:
Crizotinib is an anticancer drug. It is a potent, orally bioavailable, ATP-competitive inhibitor of the receptor tyrosine kinases (RTKs) c-Met (hepatocyte growth factor receptor), anaplastic lymphoma kinase (ALK) and ROS1 (c-ros oncogene 1). Selective for c-MET and ALK against >120 different kinases. Displays antitumor efficacy in multiple tumor models; inhibits c-MET-dependent proliferation, migration and invasion of human tumor cells in vitro. Orally bioavailable. Crizotinib was approved for treatment of a subtype of nonsmall-cell lung cancer (NSCLC) with ALK fusion mutations.
宿主来源:
Synthetic
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
450.34
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
877399-52-5
分子式:
C21H22Cl2FN5O
溶解度:
Soluble in choroform, DMSO or methanol.
促销活动
精品推荐
