| 货号:60-145 | 规格:400 ul | 目录价:¥8687.25 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CRYGD Antibody
别名:
Gamma-crystallin D, Gamma-D-crystallin, Gamma-crystallin 4, CRYGD, CRYG4
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit Ig
克隆性:
Polyclonal
纯化方式:
This antibody is purified through a protein A column, followed by peptide affinity purification.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Supplied in PBS with 0.09% (W/V) sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
Crystallins are separated into two classes:
taxon-specific, or enzyme, and ubiquitous. The latter class
constitutes the major proteins of vertebrate eye lens and maintains
the transparency and refractive index of the lens. Since lens
central fiber cells lose their nuclei during development, these
crystallins are made and then retained throughout life, making them
extremely stable proteins. Mammalian lens crystallins are divided
into alpha, beta, and gamma families; beta and gamma crystallins
are also considered as a superfamily. Alpha and beta families are
further divided into acidic and basic groups. Seven protein regions
exist in crystallins: four homologous motifs, a connecting peptide,
and N- and C-terminal extensions. Gamma-crystallins are a
homogeneous group of highly symmetrical, monomeric proteins
typically lacking connecting peptides and terminal extensions. They
are differentially regulated after early development. Four
gamma-crystallin genes (gamma-A through gamma-D) and three
pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a
genomic segment as a gene cluster. Whether due to aging or
mutations in specific genes, gamma-crystallins have been involved
in cataract formation.
Accession #:
P07320
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